Temporal context processing within hippocampal subfields
نویسندگان
چکیده
منابع مشابه
Functional Activation Within Hippocampal Subfields During Scene Memory Encoding In Temporal Lobe Epilepsy
Introduction We present, for the first time, functional activation patterns within hippocampal subfields in temporal lobe epilepsy (TLE) patients. The hippocampus is a complex structure consisting of subregions that express varied cell types, and are differentially affected by neurological disorders, including TLE. For example, dentate gyrus (DG) is one subfield that has been implicated in both...
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The unique circuitry of the hippocampus is thought to support the encoding and retrieval of context-rich episodic memories. Given the neuroanatomical differences between the hippocampal subfields, determining their functional roles during representation of contextual features in humans is an important yet unaddressed research goal. Prior studies suggest that, during the acquisition of informati...
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To clarify the anatomical organization of human memory remains a major challenge in clinical neuroscience. Experimental data suggest dentate gyrus granule cells play a major role in memory acquisition, i.e. pattern separation and rapid pattern completion, whereas hippocampal CA1 neurons are implicated in place memory and autobiographical memory retrieval. Patients with temporal lobe epilepsy pr...
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Pathology studies have shown that the anatomical subregions of the hippocampal formation are differentially affected in various neurological disorders, including temporal lobe epilepsy (TLE). Analysis of structure and function within these subregions using magnetic resonance imaging (MRI) has the potential to generate insights on disease associations as well as normative brain function. In this...
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BACKGROUND AND PURPOSE Hippocampus volumetry is a useful surrogate marker for the diagnosis of Alzheimer disease, but it seems insufficiently sensitive for the aMCI stage. We postulated that some hippocampus subfields are specifically atrophic in aMCI and that measuring hippocampus subfield volumes will improve sensitivity of MR imaging to detect aMCI. MATERIALS AND METHODS We evaluated episo...
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ژورنال
عنوان ژورنال: NeuroImage
سال: 2016
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2016.03.048